Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571850 | 0.88 | EPHX2 (0.58) | CNR1CNR2P2RY10EPHX2HDAC1 | |
| SCHEMBL6569856 | 0.88 | CNR1 (0.58) | CNR1CNR2P2RY10GGPS1GPR174 | |
| SCHEMBL6571745 | 0.87 | EPHX1 (0.44) | CNR1CNR2P2RY10HDAC3HDAC1 | |
| SCHEMBL6571796 | 0.87 | CNR1 (0.55) | CNR1CNR2P2RY10GGPS1GPR174 | |
| SCHEMBL6570365 | 0.87 | EPHX2 (0.56) | CNR1CNR2EPHX2HDAC1 | |
| SCHEMBL6569880 | 0.85 | P2RY10 (0.51) | CNR1CNR2P2RY10HDAC3HDAC1 | |
| SCHEMBL6569386 | 0.83 | EPHX2 (0.50) | EPHX2 | |
| SCHEMBL6569347 | 0.83 | EPHX2 (0.50) | EPHX2 | |
| SCHEMBL6569223 | 0.83 | EPHX2 (0.50) | EPHX2 | |
| SCHEMBL6569306 | 0.83 | EPHX2 (0.50) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156054-B1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-04-14 | — | — | EP | claimed |
| US-6495533-B1 | TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | claimed |
| EP-1156054-A1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | claimed |