Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570836 | 0.82 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6615141 | 0.76 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5713437 | 0.74 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6570942 | 0.73 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5713438 | 0.73 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5567071 | 0.73 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL2825553 | 0.72 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL5713434 | 0.71 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6569753 | 0.71 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL7154679 | 0.70 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450797-A1 | BENZOTHIAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045386-A1 | BENZOTHIAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2003-06-05 | — | — | WO | disclosed |