⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323708 | 0.84 | — | — | |
| SCHEMBL34847 | 0.84 | — | — | |
| SCHEMBL17520439 | 0.83 | — | — | |
| SCHEMBL12243371 | 0.82 | HCAR2 (0.40) | — | |
| SCHEMBL12242077 | 0.81 | HCAR2 (0.34) | — | |
| SCHEMBL13654861 | 0.78 | — | — | |
| SCHEMBL17494022 | 0.78 | — | — | |
| SCHEMBL20927578 | 0.78 | ATM (0.34) | — | |
| SCHEMBL13762292 | 0.77 | — | — | |
| SCHEMBL21737119 | 0.75 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257179-A1 | NOVEL THIAZOLES DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2011-10-20 | — | — | US | disclosed |
| EP-1372582-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO- 1,5-A] PYRIDINE AND 2-AMINO-3-HYDROXY PYRIDINE | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
| EP-1324742-A2 | OXIDATION COLORANTS CONTAINING 2-CHLORO-4-AMINOPHENOL | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002076416-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO-[1,5-A] PYRIDINE AND 2-AMINO-3-HYDROXY PYRIDINE | L'OREAL (FR) | 2002-10-03 | — | — | WO | disclosed |
| WO-2002032379-A2 | OXIDATION COLORANTS CONTAINING 2-CHLORO-4-AMINOPHENOL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-04-25 | — | — | WO | disclosed |