Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 15/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309616 | 1.00 | ITGAL (0.54) | ITGALITGB2ICAM1NOTUMMAPT | |
| SCHEMBL6567037 | 0.87 | ITGB2 (0.56) | ITGALITGB2ICAM1 | |
| SCHEMBL6311621 | 0.87 | ITGB2 (0.56) | ITGALITGB2ICAM1 | |
| SCHEMBL6309589 | 0.83 | ITGB2 (0.38) | ITGALITGB2ICAM1NOTUM | |
| SCHEMBL6309561 | 0.82 | ITGB2 (0.48) | ITGALITGB2ICAM1NOTUM | |
| SCHEMBL6570439 | 0.81 | ITGB2 (0.54) | ITGALITGB2ICAM1 | |
| SCHEMBL6311806 | 0.81 | ITGB2 (0.54) | ITGALITGB2ICAM1 | |
| SCHEMBL6569800 | 0.78 | ITGAL (0.69) | ITGALITGB2ICAM1 | |
| SCHEMBL6310199 | 0.78 | ITGAL (0.69) | ITGALITGB2ICAM1 | |
| SCHEMBL6311423 | 0.77 | ITGAL (0.58) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |