SCHEMBL6570035

SCHEMBL6570035

OC(CNC(c1cccc(Oc2cccc(OC(F)(F)C(F)F)c2)c1)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671156 0.97 CETP (0.55) CETP
SCHEMBL6568887 0.97 CETP (0.55) CETP
SCHEMBL5669781 0.96 CETP (0.48) CETP
SCHEMBL5669805 0.96 CETP (0.48) CETP
SCHEMBL5669965 0.95 CETP (0.54) CETP
SCHEMBL5670036 0.95 CETP (0.54) CETP
SCHEMBL7808089 0.95 CETP (0.54) CETP
SCHEMBL5670011 0.93 CETP (0.61) CETP
SCHEMBL6566032 0.93 CETP (0.61) CETP
SCHEMBL5669386 0.92 CETP (0.56) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469831-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS Pfizer Products Inc. (US) 2004-10-27 EP disclosed
WO-2003063832-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS PFIZER PRODUCTS INC. (US) 2003-08-07 WO disclosed