1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL6570133

C=C(Cl)Cl.C=CC(=O)OCCCC

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.85
HPGD P15428 1/20 0.85
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 1/20 0.61
ATM Q13315 1/20 0.59
HCAR2 Q8TDS4 3/20 0.52
TP53 P04637 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 3/20 0.46
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL28747122 0.96 TSHR (0.79) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1330627 0.92
SCHEMBL11582291 0.92 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1331857 0.92
SCHEMBL15037 0.92
SCHEMBL5681395 0.92 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
Vinyl Chloride SCHEMBL5607859 0.90 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL3195579 0.90 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL11810623 0.90 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4ATM
1,1-Dichloroethene SCHEMBL8510978 0.90 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105884957-A Improved polymeric composition for cement based substructures 韦斯国际解决方案股份有限公司 2016-08-24 CN claimed
CN-1385480-A Nuisanceless pollutino-resistant paint of sea water electrolytic type vinylidene chloride-vinyl chloride copolyresin series and coating system thereof CHULSANA FOREIGN SERVICE CO LT (KR) 2002-12-18 CN claimed
CN-106574094-A Compositions comprising vinylidene chloride interpolymers, films made therefrom, and articles comprising the films 陶氏环球技术有限责任公司 2017-04-19 CN disclosed
CN-101039989-B Plasticizers in Alkyl Acrylate Vinylidene Chloride Polymers DOW GLOBAL TECHNOLOGIES INC 2010-06-09 CN disclosed
CN-101039989-A Plasticizers in Alkyl Acrylate Vinylidene Chloride Polymers DOW GLOBAL TECHNOLOGIES INC (US) 2007-09-19 CN disclosed
EP-1414922-A1 DISPOSABLE WATER RESISTANT FOAMED CONCRETE COVER FOR BULK SALT University of Iowa Research Foundation (US) 2004-05-06 EP disclosed
US-6409818-B1 Disposable water resistant foamed concrete cover for bulk salt CARGILL, INCORPORATED 2002-06-25 US disclosed
WO-2001060941-A1 DISPOSABLE WATER RESISTANT FOAMED CONCRETE COVER FOR BULK SALT CARGILL, INCORPORATED (US) 2001-08-23 WO disclosed
US-5856048-A PROTECTED AGAINST FORGERY AND HAS ENHANCED SECURITY AGAINST SOME IMPROPER USE DAI NIPPON PRINTING CO., LTD. (JP) 1999-01-05 US disclosed
US-4009135-A AQUEOUS DISPERSION OF FORMALDEHYDE-AMINO-S-TRIAZINE POLYMER AND AN ADDITION POLYMER HOECHST AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed