Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652048 | 1.00 | CA1 (0.43) | CA1TP53RECQLALDH1A1KDM4E | |
| SCHEMBL6568863 | 1.00 | CA1 (0.43) | CA1TP53RECQLALDH1A1KDM4E | |
| SCHEMBL30479191 | 0.98 | CA1 (0.43) | CA1TP53RECQLALDH1A1MCL1 | |
| SCHEMBL19479825 | 0.98 | CA1 (0.43) | CA1TP53RECQLALDH1A1MCL1 | |
| SCHEMBL18239428 | 0.98 | CA1 (0.43) | CA1TP53RECQLALDH1A1MCL1 | |
| SCHEMBL1617179 | 0.98 | CA1 (0.43) | CA1TP53RECQLALDH1A1MCL1 | |
| Methylamine SCHEMBL28586411 | 0.93 | CA1 (0.41) | CA1TP53RECQLMCL1DPP4 | |
| SCHEMBL21452232 | 0.93 | TP53 (0.44) | CA1TP53RECQLALDH1A1 | |
| SCHEMBL16212102 | 0.85 | TP53 (0.47) | TP53RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL21452522 | 0.82 | CA1 (0.40) | CA1ALDH1A1MCL1MAPTTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JIANHE PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |
| EP-1280811-B1 | HYDROFORMYLATION METHOD, BRIDGED COMPOUNDS OF PHOSPHORUS, ARSENIC AND ANTIMONY AND CATALYST COMPRISING A COMPLEX OF SAID BRIDGED COMPOUNDS | BASF AG (DE) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, PAH, COMT | CA1 2743/4885TP53 3367/4885RECQL 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.