Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.57 |
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570171 | 1.00 | KDM4E (0.77) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL685201 | 0.87 | KDM4E (1.00) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6568984 | 0.83 | NTRK1 (0.78) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6568234 | 0.82 | KMT2A (0.77) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6570090 | 0.82 | NTRK1 (0.60) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6568237 | 0.82 | KMT2A (0.77) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6570093 | 0.82 | NTRK1 (0.60) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL14983736 | 0.82 | AR (0.80) | KMT2AMAPTMEN1NTRK1GCGR | |
| SCHEMBL2605876 | 0.81 | PPARG (0.66) | KDM4EKMT2AMAPTHTTLMNA | |
| SCHEMBL6568355 | 0.81 | KDM1A (0.69) | KDM4EKMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404644-A2 | NOVEL HYDRAZONES | Arpida AG, (CH) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002070464-A2 | HYDRAZONES AND THEIR THERAPEUTIC USE | ARPIDA AG (CH) | 2002-09-12 | — | — | WO | disclosed |