SCHEMBL6570517

SCHEMBL6570517

NCc1[nH]c(=O)[nH]c(=O)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMP P19971 19/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060121 0.79 TYMP (0.52) TYMP
SCHEMBL20799748 0.77 TYMP (0.50) TYMP
SCHEMBL11421684 0.77 TYMP (0.50) TYMP
SCHEMBL20599962 0.77 TYMP (0.59) TYMP
SCHEMBL6573817 0.76 TYMP (0.49) TYMP
SCHEMBL30132270 0.73 TYMP (0.52) TYMP
SCHEMBL6572727 0.73 TYMP (0.52) TYMP
SCHEMBL20599932 0.72 TYMP (0.46) TYMP
SCHEMBL20798215 0.72 TYMP (0.57) TYMP
SCHEMBL6572715 0.71 TYMP (0.57) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171005-A Tipirimidyl hydrochloride impurity compound and preparation method and application thereof 齐鲁制药有限公司 2020-05-19 CN claimed
CN-111171005-A Tipirimidyl hydrochloride impurity compound and preparation method and application thereof 齐鲁制药有限公司 2020-05-19 CN disclosed
EP-0884051-B1 CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES TAIHO PHARMACEUTICAL CO LTD (JP) 2004-12-15 EP disclosed
EP-0763529-B1 URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME TAIHO PHARMACEUTICAL CO LTD (JP) 2003-07-23 EP disclosed
US-6294535-B1 TREATING CANCER, WHICH COMPRISES ADMINISTERING TO A PATIENT IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF A URACIL DERIVATIVE TAIHO PHARMACEUTICAL CO., LTD. (JP) 2001-09-25 US disclosed
US-6255314-B1 Cancerous metastasis inhibitors containing uracil derivatives TAIHO CHARMACEUTICAL CO., LTD. (JP) 2001-07-03 US disclosed
US-6159969-A Uracil derivatives, and antitumor effect potentiator and antitumor agent containing the same TAIHO PHARMACEUTICAL CO., LTD. (JP) 2000-12-12 US disclosed
EP-0884051-A1 CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1998-12-16 EP disclosed
US-5744475-A 4-N-HET-METHYLURACIL DERIVATIVES; THYMIDINE PHOSPHORYLASE INHIBITORS TAIHO PHARMACEUTICAL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0763529-A1 URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1997-03-19 EP disclosed