Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335329 | 0.93 | CAPN1 (0.47) | CAPN1CTSBTAS1R3TAS1R1MMP9 | |
| SCHEMBL1335331 | 0.93 | CAPN1 (0.47) | CAPN1CTSBTAS1R3TAS1R1MMP9 | |
| SCHEMBL1334128 | 0.87 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSSBCHE | |
| SCHEMBL1334129 | 0.87 | CAPN1 (0.61) | CAPN1CTSBCTSKCTSSBCHE | |
| SCHEMBL1335154 | 0.73 | CAPN1 (0.78) | CAPN1CTSBCTSKCTSS | |
| SCHEMBL1335152 | 0.73 | CAPN1 (0.78) | CAPN1CTSBCTSKCTSS | |
| SCHEMBL7787050 | 0.68 | CAPN1 (0.60) | CAPN1CTSBCTSKHDAC6CTSS | |
| SCHEMBL7380235 | 0.68 | CAPN1 (0.60) | CAPN1CTSBCTSKHDAC6CTSS | |
| SCHEMBL1333615 | 0.67 | CAPN1 (0.53) | CAPN1CTSBCTSKHDAC6CTSS | |
| SCHEMBL1333613 | 0.67 | CAPN1 (0.53) | CAPN1CTSBCTSKHDAC6CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073641-B1 | NEW SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2004-04-14 | — | — | EP | disclosed |