Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310163 | 0.83 | MEN1 (0.68) | FFAR1MEN1ALDH1A1MAPTTHRB | |
| SCHEMBL20565351 | 0.82 | MAOB (0.56) | FFAR1MEN1ALDH1A1MAPTTHRB | |
| SCHEMBL13123460 | 0.81 | FFAR1 (0.56) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL28079813 | 0.81 | MAOB (0.58) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL8167077 | 0.81 | MAOB (0.58) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL12342039 | 0.81 | SYK (0.52) | MEN1ALDH1A1MAPTTHRBKMT2A | |
| SCHEMBL5287947 | 0.81 | FFAR1 (0.62) | SPHK2SPHK1FFAR1MEN1ALDH1A1 | |
| SCHEMBL14032176 | 0.80 | BCHE (0.64) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL29683508 | 0.80 | BCHE (0.64) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL9145377 | 0.80 | POLB (0.51) | MEN1MAPTKMT2AGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156054-B1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6495533-B1 | TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1156054-A1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |