Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6574673 | 0.98 | MAPT (0.49) | MAPTSMN1; SMN2L3MBTL1PGRLMNA | |
| Hydrochloric Acid SCHEMBL6572452 | 0.85 | HSD17B3 (0.51) | SMN1; SMN2L3MBTL1LMNACYP1A2CYP3A4 | |
| SCHEMBL6571330 | 0.81 | MAPT (0.49) | MAPTSMN1; SMN2L3MBTL1LMNAHPGD | |
| SCHEMBL4569792 | 0.81 | MAPT (0.68) | MAPTSMN1; SMN2L3MBTL1PGRLMNA | |
| Hydrochloric Acid SCHEMBL6574158 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2RELAMEN1USP2 | |
| SCHEMBL1708791 | 0.80 | KMT2A (0.48) | MAPTLMNATSHRHPGDALDH1A1 | |
| SCHEMBL221282 | 0.78 | MAPT (0.57) | MAPTSMN1; SMN2L3MBTL1LMNACYP1A2 | |
| Butane SCHEMBL11694245 | 0.75 | MAPT (0.53) | MAPTSMN1; SMN2L3MBTL1LMNACYP1A2 | |
| SCHEMBL3787112 | 0.75 | MAPT (0.49) | MAPTSMN1; SMN2RELAPKMCYP19A1 | |
| SCHEMBL10389933 | 0.74 | SMN1; SMN2 (0.83) | MAPTSMN1; SMN2L3MBTL1PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |