Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.82 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317420 | 0.90 | PTPN1 (1.00) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4317427 | 0.90 | PTPN1 (1.00) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6574724 | 0.90 | PTPN1 (1.00) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6574992 | 0.89 | PTPN1 (0.92) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6572512 | 0.89 | PTPN1 (0.88) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6572619 | 0.88 | PTPN1 (0.86) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6572803 | 0.88 | PTPN1 (0.92) | PTPN1KLKB1 | |
| SCHEMBL6571540 | 0.87 | PTPN1 (0.84) | PTPN1 | |
| SCHEMBL6572915 | 0.87 | PTPN1 (0.95) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6573285 | 0.86 | PTPN1 (0.87) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | claimed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |