SCHEMBL6572672

SCHEMBL6572672

Cc1ccc(NC(=O)Cn2cc[n+](CC(=O)Nc3ccc(C)cc3O)c2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.50
GAA P10253 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CXCR2 P25025 1/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5526645 0.99 HPGD (0.49) HPGDGAANPC1RAB9ACXCR2
SCHEMBL6575298 0.94 HPGD (0.45) HPGDGAANPC1RAB9ACXCR2
Hydrochloric Acid SCHEMBL6572037 0.93 HPGD (0.44) HPGDGAANPC1RAB9ACXCR2
SCHEMBL6574937 0.88 HPGD (0.40) HPGDGAANPC1RAB9AKMT2A
Hydrochloric Acid SCHEMBL6571886 0.87 HPGD (0.40) HPGDGAANPC1RAB9AKMT2A
SCHEMBL6573686 0.86 RAD52 (0.39) HPGDKMT2AMEN1CYP1A2CYP2C19
SCHEMBL6944270 0.85 HPGD (0.52) HPGDGAANPC1RAB9ACXCR2
SCHEMBL6575606 0.85 POLB (0.39) HPGDNPC1RAB9AKMT2AMEN1
Hydrochloric Acid SCHEMBL6572916 0.85 RAD52 (0.39) HPGDKMT2AMEN1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL6941314 0.84 HPGD (0.51) HPGDGAANPC1RAB9ACXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP claimed
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP disclosed
EP-1066263-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP disclosed
WO-2000043368-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO disclosed