Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.84 |
| ▸ | PPARG | P37231 | 15/20 | 0.84 |
| ▸ | PPARD | Q03181 | 12/20 | 0.84 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394964 | 1.00 | PPARA (0.84) | PPARAPPARGPPARDGAALMNA | |
| SCHEMBL5381119 | 0.91 | PPARG (1.00) | PPARAPPARGPPARDGAALMNA | |
| SCHEMBL5381122 | 0.91 | PPARG (1.00) | PPARAPPARGPPARDGAALMNA | |
| SCHEMBL5374988 | 0.91 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL5380050 | 0.90 | PPARA (0.84) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL5380384 | 0.90 | PPARG (0.84) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL5380404 | 0.90 | PPARG (0.84) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL5380055 | 0.90 | PPARA (0.84) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL5389427 | 0.89 | PPARA (0.82) | PPARAPPARGPPARDLMNA | |
| SCHEMBL5400440 | 0.89 | PPARA (0.82) | PPARAPPARGPPARDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |