SCHEMBL6573739

SCHEMBL6573739

CO[PH](=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13265365 0.73
Chloromethane SCHEMBL11603207 0.70
SCHEMBL29591 0.67
SCHEMBL9653042 0.67
SCHEMBL258425 0.67
Ethane SCHEMBL11418141 0.64
SCHEMBL10619963 0.64
SCHEMBL9985741 0.64
SCHEMBL258624 0.64
SCHEMBL258459 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495374-B1 SIMPLE PREPARATION METHOD FOR DIALKOXYPROPYL METHYLPHOSPHONATE JIANGSU GOOD HARVEST WEIEN AGROCHEMICAL CO LTD (CN) 2020-10-28 EP disclosed
US-10759818-B2 Simple preparation method for dialkoxypropyl methylphosphonate JIANGSU GOOD HARVEST-WEIEN AGROCHEMICAL CO., LTD (CN) 2020-09-01 US disclosed
US-20190284215-A1 SIMPLE PREPARATION METHOD FOR DIALKOXYPROPYL METHYLPHOSPHONATE JIANGSU GOOD HARVEST-WEIEN AGROCHEMICAL CO., LTD (CN) 2019-09-19 US disclosed
EP-3495374-A1 SIMPLE PREPARATION METHOD FOR DIALKOXYPROPYL METHYLPHOSPHONATE Jiangsu Good Harvest-Weien Agrochemical Co., Ltd (CN) 2019-06-12 EP disclosed
US-9543619-B2 Functionalized phosphorus containing fluoropolymers and electrolyte compositions Blue Current, Inc. (US) 2017-01-10 US disclosed
US-20160226104-A1 FUNCTIONALIZED PHOSPHORUS CONTAINING FLUOROPOLYMERS AND ELECTROLYTE COMPOSITIONS Blue Current, Inc. 2016-08-04 US disclosed
EP-0642507-B1 TRANSITION STATE ANALOGUES OF COCAINE, THEIR USE FOR PRODUCING CATALYTIC ANTIBODIES AGAINST COCAINE AND USE OF THE SAME IN DIAGNOSIS AND THERAPY UNIV COLUMBIA (US) 2004-02-04 EP disclosed
US-6566084-B1 Detecting hydrolysis of cocaine compound; obtain cocaine mixture, incubate with antibody, monitor generation of benzoic zacid THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2003-05-20 US disclosed
US-6184013-B1 ANTIBODY FOR REDUCING CONCENTRATION OF DRUG IN PATIENT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2001-02-06 US disclosed
US-5990285-A ANTIBODY CAPABLE OF BINDING A TRANSITION STATE ANALOG FOR THE HYDROLYSIS OF COCAINE BENZOYL ESTER GROUP; TREATMENT OF DRUG ABUSE, DRUG DEPENDENCE, OVERDOSES THE TRUSTEES OF COLUMBIA UNIVERSITY (US) 1999-11-23 US disclosed
EP-0666905-A4 MOLECULES WITH ANTIBODY COMBINING SITES THAT INDUCE ASYMMETRY. SCRIPPS RESEARCH INST (US) 1996-07-24 EP disclosed
WO-1996000733-A1 DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-11 WO disclosed
US-5444155-A Paratope-containing; immunoreact with a meso diester substrate ligand and catalytically hydrolyze a single predetermined ester bond to form one of a pair of enantiomers THE SCRIPPS RESEARCH INSTITUTE (US) 1995-08-22 US disclosed
EP-0666905-A1 MOLECULES WITH ANTIBODY COMBINING SITES THAT INDUCE ASYMMETRY THE SCRIPPS RESEARCH INSTITUTE (US) 1995-08-16 EP disclosed
EP-0642507-A4 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME. 1995-03-29 EP disclosed
EP-0642507-A1 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME The Trustees of Columbia University in the City of New York (US) 1995-03-15 EP disclosed
WO-1993020076-A1 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1993-10-14 WO disclosed
US-5250426-A Catalytic hydrolysis using monoclonal antibodies THE SCRIPPS RESEARCH INSTITUTE (US) 1993-10-05 US disclosed
WO-1993005146-A1 MOLECULES WITH ANTIBODY COMBINING SITES THAT INDUCE ASYMMETRY THE SCRIPPS RESEARCH INSTITUTE (US) 1993-03-18 WO disclosed
US-3961050-A Insecticidal compositions and methods of killing insects using benzylthiomethylenephosphonamidates and phosphoramidates VELSICOL CHEMICAL CORPORATION (US) 1976-06-01 US disclosed