Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 15/20 | 0.72 |
| ▸ | INMT | O95050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1682937 | 0.98 | TYMP (0.72) | TYMPINMTMAPTHTTRAB9A | |
| SCHEMBL20799905 | 0.84 | TYMP (0.70) | TYMPINMTMAPTHTTRAB9A | |
| Tipiracil SCHEMBL1682960 | 0.84 | TYMP (1.00) | TYMPINMT | |
| Tipiracil SCHEMBL1682924 | 0.82 | TYMP (1.00) | TYMP | |
| SCHEMBL14388372 | 0.81 | TYMP (0.67) | TYMPINMT | |
| SCHEMBL22103038 | 0.81 | TYMP (0.67) | TYMPINMT | |
| SCHEMBL1682949 | 0.80 | TYMP (0.65) | TYMPINMTSMN1; SMN2 | |
| SCHEMBL1682952 | 0.76 | TYMP (0.43) | TYMP | |
| SCHEMBL1682944 | 0.74 | TYMP (0.65) | TYMP | |
| SCHEMBL20799917 | 0.70 | TYMP (0.52) | TYMPINMTMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884051-B1 | CANCEROUS METASTASIS INHIBITORS CONTAINING URACIL DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2004-12-15 | — | — | EP | claimed |
| EP-0763529-B1 | URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-0763529-A1 | URACIL DERIVATIVES, AND ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1997-03-19 | — | — | EP | claimed |