Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6576017 | 0.89 | KCNH2 (0.54) | KCNH2ADRB3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6573050 | 0.88 | KCNH2 (0.70) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| Hydrochloric Acid SCHEMBL6572827 | 0.83 | KCNH2 (0.61) | KCNH2ADRB3CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6572115 | 0.79 | KCNH2 (0.57) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| Hydrochloric Acid SCHEMBL6576042 | 0.79 | KCNH2 (0.56) | KCNH2ADRB3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6573611 | 0.78 | KCNH2 (0.70) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| Hydrochloric Acid SCHEMBL6575579 | 0.77 | KCNH2 (0.78) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| SCHEMBL6574115 | 0.74 | KCNH2 (0.84) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| SCHEMBL9053008 | 0.73 | KCNH2 (0.77) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F | |
| SCHEMBL8781733 | 0.72 | KCNH2 (0.72) | KCNH2CYP1A2CYP3A4CYP2D6CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |