Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 3/20 | 0.46 |
| ▸ | CCKBR | P32239 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572625 | 0.91 | PTPN1 (0.67) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6572629 | 0.91 | PTPN1 (0.67) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6573618 | 0.90 | PTPN1 (0.59) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6571465 | 0.90 | PTPN1 (0.65) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6572831 | 0.89 | PTPN1 (0.64) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6572579 | 0.89 | PTPN1 (0.64) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6572795 | 0.89 | PTPN1 (0.61) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6573532 | 0.89 | PTPN1 (0.60) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6574701 | 0.88 | PTPN1 (0.60) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL6571334 | 0.88 | PTPN1 (0.60) | PTPN1PTPN22PTPRACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1019364-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999011606-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |