Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 11/20 | 0.63 |
| ▸ | PRKCA | P17252 | 3/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.47 |
| ▸ | CDK2 | P24941 | 8/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.47 |
| ▸ | CLK1 | P49759 | 3/20 | 0.47 |
| ▸ | CLK2 | P49760 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574862 | 1.00 | CDK1 (0.63) | CDK1PRKCACCNB1CCNB2CCNB3 | |
| SCHEMBL6576931 | 0.94 | CDK1 (0.71) | CDK1PRKCACCNB1CCNB2CCNB3 | |
| SCHEMBL6576936 | 0.94 | CDK1 (0.71) | CDK1PRKCACCNB1CCNB2CCNB3 | |
| SCHEMBL6576961 | 0.87 | CDK1 (0.70) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6574758 | 0.87 | CDK1 (0.70) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6574762 | 0.87 | CDK1 (0.70) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6576959 | 0.87 | CDK1 (0.70) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6574816 | 0.87 | CDK1 (0.71) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6574896 | 0.87 | CDK1 (0.71) | CDK1PRKCACCNE1CDK2PDGFRA | |
| SCHEMBL6574858 | 0.86 | CDK1 (0.57) | CDK1PRKCACCNB1CCNB2CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |