Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.60 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.60 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572629 | 0.93 | PTPN1 (0.67) | PTPN1PTPN22PTPRAPLGPRSS1 | |
| SCHEMBL6572625 | 0.93 | PTPN1 (0.67) | PTPN1PTPN22PTPRAPLGPRSS1 | |
| SCHEMBL6571465 | 0.91 | PTPN1 (0.65) | PTPN1PTPN22PTPRACTSSCTSK | |
| SCHEMBL7665730 | 0.90 | PTPN1 (0.60) | PTPN1PTPN22PTPRAITGB3ITGA2B | |
| SCHEMBL6572831 | 0.90 | PTPN1 (0.64) | PTPN1PTPN22PTPRAITGB3ITGA2B | |
| SCHEMBL6572579 | 0.90 | PTPN1 (0.64) | PTPN1PTPN22PTPRAITGB3ITGA2B | |
| SCHEMBL6572795 | 0.90 | PTPN1 (0.61) | PTPN1PTPN22PTPRAPLGPRSS1 | |
| SCHEMBL6574701 | 0.89 | PTPN1 (0.60) | PTPN1PTPN22PTPRAITGB3ITGA2B | |
| SCHEMBL6571334 | 0.89 | PTPN1 (0.60) | PTPN1PTPN22PTPRAITGB3ITGA2B | |
| SCHEMBL6572742 | 0.88 | PTPN1 (0.59) | PTPN1PTPN22PTPRAPLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | claimed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | disclosed |