Sugi Predict

Sugi Predict / Compounds / SCHEMBL6575033

SCHEMBL6575033

SCHEMBL6575033

CCCCCNC(=O)[C@H](Cc1ccc(OCC(=O)O)c(-c2nn[nH]n2)c1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 18/20 1.00
▸ PTPRA P18433 1/20 0.48
▸ PTPN22 Q9Y2R2 1/20 0.47
▸ CCKAR P32238 1/20 0.44
▸ CCKBR P32239 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6574804 0.86 PTPN1 (0.86) PTPN1PTPRAPTPN22
SCHEMBL6575372 0.84 PTPN1 (1.00) PTPN1PTPRAPTPN22
SCHEMBL7673343 0.84 PTPN1 (0.75) PTPN1PTPRAPTPN22
SCHEMBL7674414 0.84 PTPN1 (0.72) PTPN1PTPRAPTPN22
SCHEMBL6574868 0.82 PTPN1 (0.87) PTPN1PTPRAPTPN22
SCHEMBL7673240 0.81 PTPN1 (0.68) PTPN1
SCHEMBL6572963 0.79 PTPN1 (0.89) PTPN1PTPRAPTPN22
SCHEMBL6571372 0.79 PTPN1 (0.88) PTPN1PTPRAPTPN22
SCHEMBL7674533 0.78 PTPN1 (0.88) PTPN1PTPRAPTPN22
SCHEMBL6572424 0.78 PTPN1 (0.88) PTPN1PTPRAPTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1019364-B1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE BIOVITRUM AB (SE) 2004-06-09 — — EP claimed
US-6353023-B1 AROMATIC COMPOUNDS WITH AMIDE GROUPS PHARMACIA & UPJOHN COMPANY 2002-03-05 — — US claimed
EP-1019364-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 2000-07-19 — — EP claimed
WO-1999011606-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 1999-03-11 — — WO claimed
EP-1019364-B1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE BIOVITRUM AB (SE) 2004-06-09 — — EP disclosed
US-6410585-B1 THERAPY FOR NON-INSULIN DEPEND DIABETES BIOVITRUM AB (SE) 2002-06-25 — — US disclosed
US-6353023-B1 AROMATIC COMPOUNDS WITH AMIDE GROUPS PHARMACIA & UPJOHN COMPANY 2002-03-05 — — US disclosed
EP-1019364-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 2000-07-19 — — EP disclosed
WO-1999011606-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 1999-03-11 — — WO disclosed