SCHEMBL6575256

SCHEMBL6575256

O=C(c1ccc2cc(O)ccc2c1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.77
ESR2 Q92731 6/20 0.77
MEN1 O00255 1/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
KMT2A Q03164 1/20 0.60
CLK1 P49759 1/20 0.51
DYRK1A Q13627 1/20 0.51
DYRK1B Q9Y463 1/20 0.51
PLAU P00749 1/20 0.49
CYP1A2 P05177 1/20 0.47
F12 P00748 1/20 0.43
CES2 O00748 2/20 0.43
DEGS1 O15121 1/20 0.43
CES1 P23141 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
NR3C2 P08235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27443700 0.88 ESR1 (0.78) ESR1ESR2MEN1KMT2APLAU
SCHEMBL2112579 0.87 ESR1 (1.00) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL2114814 0.82 ESR1 (0.66) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL2112860 0.81 ESR1 (0.58) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL2113060 0.80 ESR1 (0.69) ESR1ESR2MEN1RAB9AKMT2A
SCHEMBL2111092 0.80 ESR1 (0.60) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL2112496 0.80 ESR1 (0.67) ESR1ESR2MEN1KMT2ACLK1
SCHEMBL11759091 0.80 ESR1 (0.62) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL5670526 0.79 PLAU (0.56) ESR1ESR2MEN1NPC1RAB9A
SCHEMBL9001693 0.78 NPSR1 (0.61) ESR1ESR2MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881267-B1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 2004-04-28 EP disclosed
EP-0882767-B1 BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF UENO SEIYAKU OYO KENKYUJO KK (JP) 2003-04-16 EP disclosed
US-6548703-B1 Toning agent KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2003-04-15 US disclosed
CN-1098316-C Bisazo compounds and process for the preparation thereof UENO SEIYAKU OYO KENKYUJO KK (JP) 2003-01-08 CN disclosed
US-6252104-B1 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-06-26 US disclosed
EP-1043364-A1 TONING AGENT KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2000-10-11 EP disclosed
EP-0765858-B1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-12-22 EP disclosed
US-5973126-A REACTING A 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID, AN AMIDE, OR AN ESTER THEREOF OR DERIVATIVES WITH A DIAZOTIZED AROMATIC PRIMARY AMINE; WATER RESISTANCE, CHEMICAL RESISTANCE AND SOLVENT RESISTANCE. KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-26 US disclosed
US-5965715-A Bisazo compounds and process for the preparation thereof KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-12 US disclosed
CN-1211270-A Bisazo compounds and process for the preparation thereof UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-03-17 CN disclosed
EP-0882767-A1 BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-09 EP disclosed
US-5847233-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-08 US disclosed
EP-0881267-A1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1998-12-02 EP disclosed
US-5786523-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-07-28 US disclosed
EP-0765858-A1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-04-02 EP disclosed