Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.83 |
| ▸ | PPARA | Q07869 | 17/20 | 0.83 |
| ▸ | PPARD | Q03181 | 13/20 | 0.83 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375414 | 1.00 | PPARG (0.83) | PPARGPPARAPPARDACHELMNA | |
| SCHEMBL5374986 | 0.94 | PPARG (0.85) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5381119 | 0.91 | PPARG (1.00) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5381122 | 0.91 | PPARG (1.00) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5389587 | 0.90 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL5400017 | 0.88 | PPARG (0.95) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5383860 | 0.88 | PPARG (0.95) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5377460 | 0.87 | PPARG (0.93) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5380859 | 0.87 | PPARG (0.93) | PPARGPPARAPPARDLMNAMAPT | |
| SCHEMBL5389190 | 0.86 | PPARG (0.72) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |