Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | SOX18 | P35713 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30275055 | 1.00 | PDPK1 (0.66) | PDPK1CYP1A2NPC1RAB9AFFAR1 | |
| SCHEMBL30275054 | 1.00 | PDPK1 (0.66) | PDPK1CYP1A2NPC1RAB9AFFAR1 | |
| SCHEMBL659321 | 0.90 | SMN1; SMN2 (0.63) | PDPK1CYP1A2NPC1RAB9AFFAR1 | |
| SCHEMBL658384 | 0.87 | CYP1A2 (0.53) | PDPK1CYP1A2NPC1RAB9ATDP1 | |
| SCHEMBL11538796 | 0.86 | MAPT (0.68) | PDPK1CYP1A2NPC1RAB9ATDP1 | |
| SCHEMBL28658857 | 0.86 | NPC1 (0.70) | PDPK1CYP1A2NPC1RAB9ACASP3 | |
| SCHEMBL23351593 | 0.84 | CYP1A2 (0.53) | PDPK1CYP1A2NPC1RAB9AFFAR1 | |
| SCHEMBL1217683 | 0.84 | CYP1A2 (0.80) | PDPK1CYP1A2FFAR1HDAC1HDAC8 | |
| SCHEMBL30403190 | 0.84 | CYP1A2 (0.80) | PDPK1CYP1A2FFAR1HDAC1HDAC8 | |
| SCHEMBL13386260 | 0.83 | SMN1; SMN2 (0.55) | PDPK1CYP1A2NPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102430-A | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-111807971-B | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-111807971-A | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-106478395-B | A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone | 南京理工大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-106478395-A | A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | PDPK1 109/4885CYP1A2 4611/4885NPC1 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.