Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166935 | 0.82 | GRIA4 (0.66) | GRIA4L3MBTL1 | |
| SCHEMBL6575826 | 0.81 | ESRRG (0.45) | ESRRGCNR2CNR1RORCL3MBTL1 | |
| SCHEMBL6761054 | 0.79 | GRIA4 (0.58) | GRIA4CNR1L3MBTL1 | |
| SCHEMBL5877784 | 0.78 | GRIA4 (0.55) | GRIA4CNR1L3MBTL1 | |
| SCHEMBL6565144 | 0.78 | GRIA4 (0.77) | GRIA4L3MBTL1 | |
| SCHEMBL6573834 | 0.77 | GRIA4 (0.60) | GRIA4NR3C1 | |
| SCHEMBL6573840 | 0.77 | GRIA4 (0.60) | GRIA4NR3C1 | |
| SCHEMBL6763725 | 0.76 | CYP2C19 (0.40) | GRIA4NR3C1CYP2C19 | |
| SCHEMBL5878303 | 0.74 | GRIA4 (0.64) | GRIA4NR3C1CNR2CNR1CYP2C19 | |
| SCHEMBL5877603 | 0.73 | GRIA4 (0.67) | GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
| EP-1409452-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002098846-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | GRIA4 9/4885NR3C1 699/4885ESRRG 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.