⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100810 | 0.69 | — | — | |
| SCHEMBL3538842 | 0.67 | — | — | |
| SCHEMBL3538841 | 0.67 | — | — | |
| SCHEMBL13784614 | 0.67 | — | — | |
| SCHEMBL22070187 | 0.67 | — | — | |
| Ethyne SCHEMBL28975706 | 0.65 | — | — | |
| SCHEMBL187821 | 0.63 | — | — | |
| SCHEMBL187820 | 0.63 | — | — | |
| SCHEMBL3500074 | 0.59 | — | — | |
| SCHEMBL2161868 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621654-B | TRPV1 modulator compounds | 安塔尔遗传学公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-3621950-B1 | TRPV1 MODULATOR COMPOUNDS | ANTALGENICS S L (ES) | 2021-12-15 | — | — | EP | disclosed |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | VTVX HOLDINGS II LLC | 2021-06-24 | — | — | US | disclosed |
| US-10947180-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200215073-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | HIGH POINT PHARMACEUTICALS, LLC | 2020-07-09 | — | — | US | disclosed |
| US-20200199063-A1 | TRPV1 Modulator Compounds | ANTALGENICS, S.L. (ES) | 2020-06-25 | — | — | US | disclosed |
| EP-3621950-A1 | TRPV1 MODULATOR COMPOUNDS | Antalgenics, S.L. (ES) | 2020-03-18 | — | — | EP | disclosed |
| CN-110621654-A | TRPV1 modulator compounds | 安塔尔遗传学公司 | 2019-12-27 | — | — | CN | disclosed |
| US-10471066-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2019-11-12 | — | — | US | disclosed |
| WO-2018206742-A1 | TRPV1 MODULATOR COMPOUNDS | ANTALGENICS, S.L. (ES) | 2018-11-15 | — | — | WO | disclosed |
| US-6869967-B2 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives | NOVO NORDISK A/S (DK) | 2005-03-22 | — | — | US | disclosed |
| US-20050054624-A1 | Modified, hydroxy-substituted aromatic structures having cytoprotective activity | WASHINGTON UNIVERSITY (US) | 2005-03-10 | — | — | US | disclosed |
| US-6844456-B2 | Modified, hydroxy-substituted aromatic structures having cytoprotective activity | WASHINGTON UNIVERSITY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20040143006-A1 | Novel compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC | 2004-07-22 | — | — | US | disclosed |
| EP-1330467-A2 | MODIFIED, HYDROXY-SUBSTITUTED AROMATIC STRUCTURES HAVING CYTOPROTECTIVE ACTIVITY | WASHINGTON UNIVERSITY (US) | 2003-07-30 | — | — | EP | disclosed |
| US-20030139473-A1 | Novel compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-07-24 | — | — | US | disclosed |
| US-20020103178-A1 | Modified, hydroxy-substituted aromatic structures having cytoprotective activity | WASHINGTON UNIVERSITY | 2002-08-01 | — | — | US | disclosed |
| WO-2002036605-A2 | ESTRONE-DERIVATIVES HAVING CYTOPROTECTIVE ACTIVITY | WASHINGTON UNIVERSITY (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-0510947-A1 | N-Hydroxy (thio)ureas as 5-lipoxygenase inhibitors | ELI LILLY AND COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5130485-A | For treatment of asthma, arthritis, allergy, inflammatory bowel disease, psoriasis, respiratory system disorders and antiischemic agents | ELI LILLY AND COMPANY (US) | 1992-07-14 | — | — | US | disclosed |