SCHEMBL6575970

SCHEMBL6575970

O=C(O)CC(CO)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27260660 1.00
SCHEMBL27654688 1.00
SCHEMBL28007744 0.88 CACNA2D1 (0.38)
SCHEMBL45197 0.83
SCHEMBL619735 0.83 SLC22A6 (0.47)
SCHEMBL5144811 0.80 SLC22A6 (0.45)
SCHEMBL5165804 0.80 SLC22A6 (0.45)
SCHEMBL5905658 0.80 SLC22A6 (0.45)
SCHEMBL1100230 0.80 SLC22A6 (0.45)
SCHEMBL5144412 0.80 SLC22A6 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3228830-A None JP disclosed
CN-114789055-A Preparation method and application of supported ferroferric oxide catalyst 浙江科技学院 2022-07-26 CN disclosed
EP-0967271-B1 NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE KANEKA CORP (JP) 2004-10-20 EP disclosed
US-6448052-B2 TO CONVERT ETHYL 4-CHLOROACETOACETATE USING NADPH AS A COENZYME TO PRODUCE ETHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE; SUBSTRATE SPECIFICITY, NO ACTIVITY TO ETHYL ACETOACETATE, SPECIFIED OPTIMAL PH AND TEMPERATURE; ENZYME FROM CANDIDA KANEKA CORPORATION (JP) 2002-09-10 US disclosed
US-20020006651-A1 Carbonyl reductase enzyme and methods for its use KANEKA CORPORATION 2002-01-17 US disclosed
US-6218156-B1 DNA WHICH CODES FOR ENZYME THAT CONVERTS ETHYL 4-CHLOROACETOACETATE TO ETHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE; FOR OPTICALLY ACTIVE ALCOHOLS USED AS RAW MATERIALS IN DRUG AND AGRICULTURAL CHEMICAL PRODUCTION KANEKA CORPORATION (JP) 2001-04-17 US disclosed
EP-0967271-A1 NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE KANEKA CORPORATION (JP) 1999-12-29 EP disclosed
JP-H03228830-A METHOD FOR RECOVERYING COBALT COMPOUND KYOWA YUKA KK 1991-10-09 JP disclosed