Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691543 | 0.91 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL10358866 | 0.91 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL13980023 | 0.91 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL10519979 | 0.87 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL14352056 | 0.85 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL10520143 | 0.84 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL1263491 | 0.81 | ATM (0.43) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL10520372 | 0.81 | ATM (0.39) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL16487743 | 0.81 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8087299 | 0.81 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806267-A | Liquid aromatic bisoxazoline and bisoxazine monomer mixtures and process for crosslinking using phenolics | ASHLAND OIL, INC. (US) | 1989-02-21 | — | — | US | claimed |
| EP-0866097-B1 | FLAME-RETARDANT, ANTISTATIC POLYESTER RESIN COMPOSITION | KANEKA CORP (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-6096818-A | COMPOSITION COMPRISING THERMOPLASTIC POLYESTER, BROMINE-CONTAINING FLAME RETARDANT, ANTIMONY COMPOUND, CONDUCTIVE CARBON BLACK PARTICLES | KANEKA CORPORATION (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0866097-A1 | FLAME-RETARDANT, ANTISTATIC POLYESTER RESIN COMPOSITION | KANEKA CORPORATION (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-4841002-A | Liquid aromatic bisoxazoline and disoxazine monomer mixtures cured with polyphenolic compounds | ASHLAND OIL, INC (US) | 1989-06-20 | — | — | US | disclosed |
| US-4806267-A | Liquid aromatic bisoxazoline and bisoxazine monomer mixtures and process for crosslinking using phenolics | ASHLAND OIL, INC. (US) | 1989-02-21 | — | — | US | disclosed |