Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6782593 | 0.98 | GUSB (0.50) | GUSBCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6570910 | 0.83 | NPC1 (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL27500073 | 0.79 | GUSB (0.68) | GUSBCA12CA1CA2CA9 | |
| SCHEMBL130519 | 0.77 | AHR (0.56) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL29560117 | 0.77 | AHR (0.56) | CA12CA1CA2CA9NPC1 | |
| Iodide SCHEMBL7361153 | 0.75 | AHR (0.54) | CA12CA1CA2CA9NPC1 | |
| Hydrochloric Acid SCHEMBL3325397 | 0.75 | AHR (0.54) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL6572426 | 0.74 | APP (0.56) | CA1CA2ALOX15CYP3A4CYP2C9 | |
| SCHEMBL7118466 | 0.74 | GUSB (0.50) | GUSBCA12CA1CA2CA9 | |
| SCHEMBL980348 | 0.73 | NPC1 (0.68) | CA12CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |