Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576193 | 1.00 | ACE (0.58) | ACEPPARGPPARDPPARA | |
| SCHEMBL8451627 | 1.00 | ACE (0.58) | ACEPPARGPPARDPPARA | |
| SCHEMBL6575447 | 0.91 | ACE (0.70) | ACE | |
| SCHEMBL6575444 | 0.91 | ACE (0.70) | ACE | |
| SCHEMBL6574206 | 0.91 | ACE (0.70) | ACE | |
| SCHEMBL6574200 | 0.91 | ACE (0.70) | ACE | |
| SCHEMBL6576380 | 0.89 | ACE (0.59) | ACE | |
| SCHEMBL8447318 | 0.89 | ACE (0.59) | ACE | |
| SCHEMBL6576378 | 0.89 | ACE (0.59) | ACE | |
| SCHEMBL5695595 | 0.89 | ACE (0.72) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |