SCHEMBL6576550

SCHEMBL6576550

CC(C)CNC(=O)O.CC(C)CNC(=O)O.CC(C)CNC(=O)O.c1cnnnc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.65
CYP2D6 P10635 1/20 0.65
ALDH1A1 P00352 5/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 6/20 0.39
MMP1 P03956 1/20 0.38
MMP8 P22894 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
RAB9A P51151 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
LMNA P02545 1/20 0.36
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL402167 0.81
SCHEMBL6576548 0.78 CYP2C19 (0.74) CYP2C19CYP2D6ALDH1A1KMT2AMEN1
SCHEMBL6578550 0.74 TSHR (0.48) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL910050 0.73 CYP2C19 (0.81) CYP2C19CYP2D6ALDH1A1KMT2AMEN1
Bromobenzene SCHEMBL27905968 0.72 CYP2C19 (0.63) CYP2C19CYP2D6ALDH1A1KMT2AMEN1
SCHEMBL6578848 0.71 KMT2A (0.32) ALDH1A1KMT2AMEN1GAASMN1; SMN2
Lactic Acid SCHEMBL28812308 0.70 TP53 (0.55) CYP2C19CYP2D6ALDH1A1CYP1A2LMNA
Isopropylamine SCHEMBL3793497 0.69 CYP2C19 (0.74) CYP2C19CYP2D6ALDH1A1KMT2AMEN1
Isopropylamine SCHEMBL3793495 0.69 CYP2C19 (0.74) CYP2C19CYP2D6ALDH1A1KMT2AMEN1
Bicarbonate SCHEMBL9005252 0.68 CA1 (0.36) KMT2AMEN1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930303-B1 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECH CORP (US) 2004-02-04 EP disclosed
EP-0933371-B1 N-halo acid amides CYTEC TECH CORP (US) 2003-04-09 EP disclosed
EP-0565774-B1 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECH CORP (US) 2001-03-28 EP disclosed
EP-0933371-A1 N-halo acid amides CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933370-A1 Tris-(2,2,6,6-tetramethyl-piperid-4-yl-aminocarbonyl)melamine CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0933369-A1 Tris-(omega-haloacyl)melamines CYTEC TECHNOLOGY CORP. (US) 1999-08-04 EP disclosed
EP-0930303-A2 A process for preparing isocyanate compounds from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1999-07-21 EP disclosed
US-5571915-A Process for preparing amide derivatives from haloaminotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1996-11-05 US disclosed
US-5405959-A Haloaminotraizines and acid halides CYTEC TECHNOLOGY CORP. (US) 1995-04-11 US disclosed
US-5288865-A Process for preparing amide derivatives from haloaminotriazines and acid halides AMERICAN CYANAMID COMPANY (US) 1994-02-22 US disclosed
EP-0565774-A2 Process for preparing amide derivatives from halominotriazines and acid halides CYTEC TECHNOLOGY CORP. (US) 1993-10-20 EP disclosed
EP-0541966-A2 Process for preparing amide derivatives from halomines and acid halides AMERICAN CYANAMID COMPANY (US) 1993-05-19 EP disclosed