Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578832 | 0.94 | TSHR (0.47) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL27474981 | 0.86 | TSHR (0.56) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6577290 | 0.85 | MAPT (0.43) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6582116 | 0.81 | TSHR (0.50) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6578812 | 0.81 | ESR1 (0.42) | TSHRALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL28620461 | 0.79 | TSHR (0.70) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL28620465 | 0.79 | TSHR (0.70) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6581322 | 0.79 | TSHR (0.47) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL27474980 | 0.79 | TSHR (0.49) | TSHRALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL6579842 | 0.79 | MEN1 (0.45) | TSHRALDH1A1LMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |