Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925046 | 0.85 | CYP2D6 (0.50) | ESR1LMNACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11325699 | 0.85 | FFAR1 (0.49) | LMNACYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25152385 | 0.84 | TAAR1 (0.55) | LMNACYP2D6CYP2C9CYP2C19CHRM2 | |
| SCHEMBL25152144 | 0.84 | TAAR1 (0.55) | LMNACYP2D6CYP2C9CYP2C19CHRM2 | |
| SCHEMBL1234229 | 0.84 | TAAR1 (0.55) | LMNACYP2D6CYP2C9CYP2C19CHRM2 | |
| SCHEMBL15592467 | 0.83 | FFAR1 (0.50) | LMNACYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL25411615 | 0.82 | ESR1 (0.47) | ESR1LMNACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7169658 | 0.81 | FFAR1 (0.55) | MAPTPDCD1CD274L3MBTL1PLA2G1B | |
| SCHEMBL11340542 | 0.80 | PTGS1 (0.59) | ESR1LMNACYP2C9CHRM1PTGS1 | |
| SCHEMBL2431870 | 0.80 | KCNA5 (0.48) | ESR1LMNACYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313559-A4 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES BOSTON COLLEGE (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1313559-A2 | RECYCLABLE METATHESIS CATALYSTS | Trustees of Boston College (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002014376-A2 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES OF BOSTON COLLEGE (US) | 2002-02-21 | — | — | WO | disclosed |