Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 14/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576921 | 1.00 | CDK1 (0.68) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6574978 | 0.93 | CDK1 (0.76) | CDK1PDGFRACCNE1CDK2PRKCA | |
| SCHEMBL6574979 | 0.93 | CDK1 (0.76) | CDK1PDGFRACCNE1CDK2PRKCA | |
| SCHEMBL6576093 | 0.92 | CDK1 (0.64) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6576102 | 0.92 | CDK1 (0.64) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6576038 | 0.91 | CDK1 (0.70) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6576046 | 0.91 | CDK1 (0.70) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6574832 | 0.91 | CDK1 (0.70) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6574829 | 0.91 | CDK1 (0.70) | CDK1SRCPDGFRACCNE1CDK2 | |
| SCHEMBL6576044 | 0.90 | CDK1 (0.71) | CDK1SRCPDGFRACCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | disclosed |