Sugi Predict

Sugi Predict / Compounds / Carbamic Acid

Carbamic Acid

Carbamic Acid

SCHEMBL6577040

CCn1cnc2c(Nc3ccc(S(=O)(=O)NC4CCCCC4)cc3)nc(NC3CCCCC3)nc21.NC(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CDK1 P06493 14/20 0.58
▸ SRC P12931 1/20 0.55
▸ PRKCA P17252 2/20 0.51
▸ PDGFRA P16234 4/20 0.50
▸ CDK2 P24941 4/20 0.50
▸ CCNE1 P24864 3/20 0.50
▸ SYK P43405 1/20 0.50
▸ EGFR P00533 1/20 0.50
▸ FLT3 P36888 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6574779 0.92 CDK1 (0.70) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6576275 0.92 CDK1 (0.70) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6574776 0.92 CDK1 (0.70) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6576296 0.92 CDK1 (0.70) CDK1SRCPRKCAPDGFRACDK2
Carbamic Acid SCHEMBL6578572 0.90 CDK1 (0.54) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6577121 0.90 CDK1 (0.57) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6577116 0.90 CDK1 (0.57) CDK1SRCPRKCAPDGFRACDK2
Carbamic Acid SCHEMBL6576937 0.90 CDK1 (0.54) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6576173 0.88 CDK1 (0.74) CDK1SRCPRKCAPDGFRACDK2
SCHEMBL6574867 0.88 CDK1 (0.74) CDK1SRCPRKCAPDGFRACDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1153024-B1 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS NOVARTIS AG (CH) 2004-04-28 — — EP claimed