SCHEMBL6578062

SCHEMBL6578062

O=C(O)O[C@H]1CC2CCCCC2N1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.35
CHRM4 P08173 5/20 0.35
CHRM3 P20309 5/20 0.35
CHRM1 P11229 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5700618 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10818536 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10766954 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL7438221 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10588318 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL5183989 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL10817753 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL2460430 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL9326179 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1
SCHEMBL3375155 1.00 CHRM2 (0.35) CHRM2CHRM4CHRM3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140826-B1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR ABBOTT GMBH & CO KG (DE) 2004-05-06 EP claimed
EP-0236307-B1 ANTIHYPERTENSIVE AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF THE AGENTS AND COMPOSITIONS SCHERING CORPORATION (US) 1991-04-17 EP claimed
EP-0278530-A2 Amino acid derivatives, process for their preparation, agents containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-17 EP claimed
EP-0115345-B1 PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-07 EP claimed
EP-0115345-A1 Process for the resolution of racemic optically active bicyclic imino-alpha-carboxylic acid esters and use of the compounds obtainable in this way for the synthesis of carboxyalkyl dipeptides HOECHST AKTIENGESELLSCHAFT (DE) 1984-08-08 EP claimed
EP-1140826-B1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR ABBOTT GMBH & CO KG (DE) 2004-05-06 EP disclosed
EP-1140826-B1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR ABBOTT GMBH & CO KG (DE) 2004-05-06 EP disclosed
EP-1140826-A1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR BASF AKTIENGESELLSCHAFT (DE) 2001-10-10 EP disclosed
WO-2000040555-A1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR BASF AKTIENGESELLSCHAFT (DE) 2000-07-13 WO disclosed