Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444713 | 0.94 | MRGPRX4 (0.56) | CYP11B1CYP11B2MRGPRX4PLAUGSK3B | |
| SCHEMBL60040 | 0.94 | MRGPRX4 (0.56) | CYP11B1CYP11B2MRGPRX4PLAUGSK3B | |
| SCHEMBL3456924 | 0.93 | MRGPRX4 (0.52) | CYP11B1CYP11B2MRGPRX4PLAUGSK3B | |
| SCHEMBL6831985 | 0.88 | CYP11B1 (0.52) | CYP11B1CYP11B2MRGPRX4PLAUGSK3B | |
| SCHEMBL7393 | 0.87 | CA1 (0.57) | GSK3BTSHRNAMPTPOLBMAPT | |
| Charcoal, Activated SCHEMBL31430427 | 0.85 | CA1 (0.55) | GSK3BTSHRNAMPTPOLBMAPT | |
| SCHEMBL7822720 | 0.84 | PLAU (0.61) | CYP11B1CYP11B2MRGPRX4PLAUGSK3B | |
| SCHEMBL6659038 | 0.83 | PLAU (0.60) | PLAUNAMPT | |
| SCHEMBL7825418 | 0.83 | PLAU (0.67) | CYP11B1CYP11B2MRGPRX4PLAU | |
| SCHEMBL7069395 | 0.83 | TSHR (0.61) | CYP11B1CYP11B2TSHRNAMPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097555-A1 | Concomitant drugs | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097555-A1 | Concomitant drugs | TNF, CHUK, CNKSR1 | CYP11B1 455/4885CYP11B2 343/4885MRGPRX4 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.