Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581471 | 0.86 | TOP2A (0.42) | STAT3HTTALDH1A1KDM4EPIM1 | |
| SCHEMBL7008763 | 0.86 | STAT3 (0.47) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7007194 | 0.85 | STAT3 (0.54) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20912569 | 0.84 | STAT3 (0.47) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7005444 | 0.82 | STAT3 (0.61) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19728864 | 0.81 | STAT3 (0.45) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19728813 | 0.81 | STAT3 (0.45) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19728865 | 0.81 | STAT3 (0.45) | STAT3HTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6576283 | 0.80 | TOP1 (0.43) | STAT3HTTALDH1A1KDM4EKMT2A | |
| SCHEMBL7003480 | 0.79 | STAT3 (0.52) | STAT3HTTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897919-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6211375-B1 | IMPROVED INTESTINAL ABSORPTION | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0897919-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-02-24 | — | — | EP | disclosed |