SCHEMBL6579357

SCHEMBL6579357

CCCCCCCCOc1c(O)c2ccc([N+](=O)[O-])cc2n(C)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.48
ACHE P22303 1/20 0.48
CNR2 P34972 1/20 0.48
MAPT P10636 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP19A1 P11511 4/20 0.43
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 2/20 0.41
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.40
CYSLTR1 Q9Y271 1/20 0.40
KCNH2 Q12809 1/20 0.40
GSK3B P49841 2/20 0.40
ESR1 P03372 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7989259 1.00 CNR1 (0.48) CNR1ACHECNR2MAPTMEN1
SCHEMBL6579208 1.00 CNR1 (0.48) CNR1ACHECNR2MAPTMEN1
SCHEMBL7988394 0.96 MAPT (0.45) CNR1ACHECNR2MAPTMEN1
SCHEMBL7964620 0.91 CNR1 (0.53) CNR1ACHECNR2MAPTMEN1
SCHEMBL7988735 0.91 CNR1 (0.48) CNR1ACHECNR2MAPTMEN1
SCHEMBL7998924 0.90 CNR1 (0.51) CNR1ACHECNR2MAPTMEN1
SCHEMBL7997356 0.90 CNR1 (0.51) CNR1ACHECNR2MAPTMEN1
SCHEMBL8004570 0.89 CNR2 (0.49) CNR1ACHECNR2MAPTMEN1
SCHEMBL8001946 0.89 CNR2 (0.47) CNR1ACHECNR2MAPTMEN1
SCHEMBL8004184 0.89 CNR2 (0.49) CNR1ACHECNR2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1185245-C Quinolinone glucoside, its preparing method and antitransformation reaction agent DANIPPON INKA ND CHEMICALS INC (JP) 2005-01-19 CN disclosed
EP-0927718-B1 Quinolinone derivative, method for preparing the same, and anti-allergic agent DAINIPPON INK & CHEMICALS (JP) 2004-02-25 EP disclosed
EP-0933378-B1 Quinolinone glycoside, production process, and anti-allergic agent DAINIPPON INK & CHEMICALS (JP) 2003-04-09 EP disclosed
US-6271416-B1 O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-08-07 US disclosed
US-6242425-B1 SINAPIC ACID GLYCOSIDE INTERMEDIATES DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-05 US disclosed
US-6136822-A ETHER, HYDROXY QUINOLINONE COMPOUNDS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-10-24 US disclosed
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US disclosed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP disclosed
CN-1228436-A Quinolinone glucoside, its preparing method and antitransformation reaction agent DAINIPPON INK & CHEMICALS (JP) 1999-09-15 CN disclosed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US disclosed
EP-0933378-A1 Quinolinone glycoside, production process, and anti-allergic agent DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-04 EP disclosed
EP-0927718-A1 Quinolinone derivative, method for preparing the same, and anti-allergic agent DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-07-07 EP disclosed
EP-0785190-A2 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-07-23 EP disclosed