Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997564 | 0.96 | TP53 (0.50) | NR1H4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7997469 | 0.91 | NR1H4 (0.52) | NR1H4TP53MEN1KMT2A | |
| SCHEMBL8001670 | 0.91 | MEN1 (0.53) | NR1H4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8002281 | 0.91 | MEN1 (0.53) | NR1H4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7988822 | 0.90 | TP53 (0.48) | NR1H4TP53MEN1KMT2AKDM4E | |
| SCHEMBL7998977 | 0.88 | TP53 (0.46) | NR1H4TP53MEN1KMT2AKDM4E | |
| SCHEMBL6579035 | 0.87 | NPC1 (0.46) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8000975 | 0.85 | MEN1 (0.49) | NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8000665 | 0.85 | MEN1 (0.51) | NR1H4MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7975873 | 0.84 | MAPT (0.52) | TP53MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1158265-C | Quinoline ketone derivant and antianaphylaction using same as active substance | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| CN-1095834-C | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2002-12-11 | — | — | CN | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| CN-1275564-A | Quinoline ketone derivant and antianaphylaction using same as active substance | DAINIPPON INK & CHEMICALS (JP) | 2000-12-06 | — | — | CN | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |
| CN-1163268-A | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | LAINIPPON INK AND CHEMICALC IN (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |