⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578586 | 0.84 | — | — | |
| SCHEMBL2511572 | 0.78 | — | — | |
| SCHEMBL2919923 | 0.75 | — | — | |
| SCHEMBL2916436 | 0.75 | — | — | |
| SCHEMBL7469753 | 0.75 | — | — | |
| SCHEMBL2919500 | 0.75 | GLI1 (0.33) | — | |
| SCHEMBL5622915 | 0.70 | BCHE (0.38) | — | |
| SCHEMBL4684662 | 0.69 | ABL1 (0.40) | — | |
| SCHEMBL2617044 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL13165462 | 0.68 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005458-B1 | CARBOSTYRIL DERIVATIVES FOR INHIBITING SKIN ERYTHEMA AND/OR SKIN PIGMENTATION | OTSUKA PHARMA CO LTD (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6133264-A | Carbostyril derivatives for inhibiting skin erythema and/or skin pigmentation | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-1005458-A1 | CARBOSTYRIL DERIVATIVES FOR INHIBITING SKIN ERYTHEMA AND/OR SKIN PIGMENTATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999009011-A1 | CARBOSTYRIL DERIVATIVES FOR INHIBITING SKIN ERYTHEMA AND/OR SKIN PIGMENTATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-02-25 | — | — | WO | disclosed |