SCHEMBL6580106

SCHEMBL6580106

CCCCCCCCCCCCCCC1OC1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
CES2 O00748 1/20 0.47
ABHD16A O95870 1/20 0.45
PRKCA P17252 4/20 0.45
DAGLA Q9Y4D2 1/20 0.45
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.42
FASN P49327 1/20 0.42
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCD Q05655 1/20 0.41
PRKD1 Q15139 1/20 0.41
PPARG P37231 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887138 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15656548 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15657689 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL14718758 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15655302 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15659839 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15658403 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL15660716 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL4653719 1.00 CYP1A2 (0.50) CYP1A2CES2ABHD16APRKCADAGLA
SCHEMBL3923431 0.98 CYP1A2 (0.48) CYP1A2CES2ABHD16APRKCADAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412309-B1 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEM CO (US) 2015-04-29 EP claimed
EP-1412309-A2 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2004-04-28 EP claimed
US-6693219-B2 PREVENTING FLUOROPHOSPHITE LIGANDS HYDROLYSIS BY ADDING AN EPOXIDE; CATALYTIC HYDROFORMYLATION OF ALPHA-OLEFIN, HYDROGEN, CARBON MONOXIDE FOR PRODUCING ALDEHYDES EASTMAN CHEMICAL COMPANY 2004-02-17 US claimed
US-20030018220-A1 Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes EASTMAN CHEMICAL COMPANY 2003-01-23 US claimed
WO-2002098825-A2 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2002-12-12 WO claimed
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
US-6740317-B1 AQUEOUS HAIR CARE COMPOSITION COMPRISING MACROCYCLIC LACTONE AND EICOSANOATE ESTER MELALEUCA, INC. 2004-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018220-A1 Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes CYP2F1, CYP4F2, CYP4F11 CYP1A2 76/4885CES2 883/4885ABHD16A 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.