SCHEMBL6580156

SCHEMBL6580156

N#CC/C=C/CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6207080 1.00
SCHEMBL818468 0.83
SCHEMBL818467 0.83
SCHEMBL819793 0.83
SCHEMBL16369047 0.73 TSHR (0.53)
SCHEMBL9882909 0.73
SCHEMBL8273303 0.73
SCHEMBL7230172 0.71
SCHEMBL5311436 0.71
SCHEMBL13660116 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111668549-B Additive for electrolyte, electrolyte and battery material 广州天赐高新材料股份有限公司 2021-07-06 CN disclosed
CN-111668549-A Additive for electrolyte, electrolyte and battery material 广州天赐高新材料股份有限公司 2020-09-15 CN disclosed
EP-0948512-B1 METHOD OF SYNTHESIZING PHOSPHOROTHIOATE OLIGONUCLEOTIDES ISIS PHARMACEUTICALS INC (US) 2004-10-06 EP disclosed
US-6780989-B2 HYBRID OLIGONUCLEOTIDE ISIS PHARMACEUTICALS, INC. 2004-08-24 US disclosed
EP-0983233-B1 REAGENT USEFUL FOR SYNTHESIZING SULFURIZED OLIGONUCLEOTIDE ANALOGS ISIS PHARMACEUTICALS INC (US) 2004-05-06 EP disclosed
US-20030114662-A1 Method of synthesizing phosphorothioate oligonucleotides ISIS PHARMACEUTICALS, INC. 2003-06-19 US disclosed
US-20020128466-A1 Method of synthesizing phosphorothioate oligonucleotides ISIS PHARMACEUTICALS, INC. 2002-09-12 US disclosed
US-6403781-B2 REACTING A PHOSPHORDIAMIDITE WITH A SUPPORT-BOUND SYNTHON TO FORM A SUPPORT BOUND PHOSPHORAMIDITE, PROTECTING TO FORM A SUPPORT BOUND PHOSHITE, SULFURIZING THE PHOSPHITE TO FORM A PROTECTED PHOSPHORTHIOATE AND DEPROTECTING ISIS PHARMACEUTICALS, INC. 2002-06-11 US disclosed
US-6399831-B1 THIODICARBONIC ACID DIESTER POLYSULFIDE ISIS PHARMACEUTICALS, INC. 2002-06-04 US disclosed
US-20010003132-A1 Method of synthesizing phosphorothioate oligonucleotides ISIS PHARMACEUTICALS, INC. 2001-06-07 US disclosed
US-5760209-A Protecting group for synthesizing oligonucleotide analogs ISIS PHARMACEUTICALS, INC. (US) 1998-06-02 US disclosed
US-5708180-A CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME BAYER AKTIENGESELLSCHAFT (DE) 1998-01-13 US disclosed
US-5705621-A Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same ISIS PHARMACEUTICALS, INC. (US) 1998-01-06 US disclosed
US-5637751-A REACTING IN LIQUID PHASE 2-BUTENE-1,4-DIOL AND/OR 3-BUTENE-1,2-DIOL WITH HYDROGEN CYANIDE IN PRESENCE OF MOLTEN CATALYST COMPRISING CUPROUS CHLORIDE OR BROMIDE AND NON-AROMATIC AMINE HYDROHALIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-10 US disclosed
EP-0612720-B1 Process for producing 1,4-dicyano-2-butene SUMITOMO CHEMICAL CO (JP) 1997-01-08 EP disclosed
EP-0563859-B1 Process for producing 1,4-dicyano-2-butene and catalyst therefor SUMITOMO CHEMICAL CO (JP) 1996-09-11 EP disclosed
EP-0702003-A2 Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes BAYER AG (DE) 1996-03-20 EP disclosed
US-5463103-A Reacting butene derivative with hydrogen cyanide in presence of catalyst prepared from cuprous halide, lower alkylamine hydrohalide and Lewis acid or basic acetate, carbonate or bicarbonate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-31 US disclosed
EP-0612720-A1 Process for producing 1,4-dicyano-2-butene SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-31 EP disclosed
EP-0563859-A2 Process for producing 1,4-dicyano-2-butene and catalyst therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-10-06 EP disclosed