Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 4/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464003 | 0.79 | MAP2K4 (0.55) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL27534314 | 0.77 | MAP2K4 (0.50) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL18770438 | 0.72 | MAP2K4 (0.55) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL14809717 | 0.72 | MAP2K4 (0.55) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL22819364 | 0.70 | MAP2K4 (1.00) | MAP2K4LRRK2IDO1PIM1CLK2 | |
| SCHEMBL10981820 | 0.70 | MAP2K4 (0.52) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL28058405 | 0.69 | CYP2A6 (0.53) | MAP2K4LRRK2ALKIDO1PIM1 | |
| SCHEMBL11991175 | 0.69 | CYP2A6 (0.56) | LRRK2ALKPIM1CHEK1AURKA | |
| SCHEMBL2322659 | 0.69 | AKT2 (0.67) | LRRK2ALKPIM1CHEK1AURKA | |
| SCHEMBL1436058 | 0.68 | ALK (1.00) | MAP2K4LRRK2ALKPIM1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080084-B1 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1080084-A2 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6087513-A | REACTION OF ALLYL ARYL ETHER WITH HYDROGEN PEROXIDE IN THE PRESENCE OF TRANSITION METALS FOR OXIDATION | THE DOW CHEMICAL COMPANY (US) | 2000-07-11 | — | — | US | disclosed |
| WO-1999062894-A2 | PROCESS FOR EPOXIDATION OF ARYL ALLYL ETHERS | THE DOW CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |