SCHEMBL6580293

SCHEMBL6580293

CC(C)(C)OC(=O)N(CCBr)C(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
CA14 Q9ULX7 2/20 0.37
DGAT1 O75907 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
SSTR4 P31391 1/20 0.32
AKT1 P31749 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3882477 0.88 HDAC6 (0.39) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL19153077 0.86 CA14 (0.41) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL8480025 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL26962278 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL5360201 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL9050850 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL100090 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL960818 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL9051516 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1
SCHEMBL2369243 0.84 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596535-A1 DRUG FOR TREATING HUMAN TUMOR BY ERF3A TARGETED PROTEIN DEGRADATION MECHANISM Suzhou Degen Bio-Medical Co, Ltd. (CN) 2025-08-06 EP disclosed
US-20250213701-A1 MEDICAMENT FOR TREATING HUMAN TUMOR BASED ON ERF3A-TARGETING PROTEOLYSIS MECHANISM SUZHOU DEGEN BIO-MEDICAL CO., LTD. (CN) 2025-07-03 US disclosed
CN-118119598-A Medicine for treating human tumor by eRF3a targeting protein degradation mechanism 苏州德亘生物医药有限公司 2024-05-31 CN disclosed
CN-117801051-A Medicine for treating human tumor by eRF3a targeting protein degradation mechanism 苏州德亘生物医药有限公司 2024-04-02 CN disclosed
EP-0990653-B1 2-OXOIMIDAZOLE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-09-15 EP disclosed
EP-1221443-B1 SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-09-01 EP disclosed
US-6699880-B1 STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS BANYU PHARMACEUTICAL CO., LTD. (JP) 2004-03-02 US disclosed
EP-1221443-A1 SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-07-10 EP disclosed
US-6258825-B1 ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION BANYU PHARMACEUTICAL CO., LTD. (JP) 2001-07-10 US disclosed
EP-0990653-A1 2-OXOIMIDAZOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213701-A1 MEDICAMENT FOR TREATING HUMAN TUMOR BASED ON ERF3A-TARGETING PROTEOLYSIS MECHANISM XIAP, TP53, UBE3A HDAC6 2324/4885HDAC1 3482/4885HDAC2 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.