Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | AHR | P35869 | 2/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376106 | 0.98 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL107104 | 0.98 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL6580411 | 0.96 | MEN1 (0.60) | MEN1KMT2AMAPTCYP3A4AHR | |
| Sulfurous Acid SCHEMBL30338559 | 0.90 | MAPT (0.53) | MEN1KMT2AMAPTCYP3A4AHR | |
| Sulfurous Acid SCHEMBL27843073 | 0.89 | MEN1 (0.51) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Acetic Acid SCHEMBL30486253 | 0.86 | MAPT (0.61) | MEN1KMT2AMAPTCYP3A4AHR | |
| Sulfurous Acid SCHEMBL468351 | 0.86 | MAPT (0.50) | MEN1KMT2AMAPTCYP3A4AHR | |
| Tert-Butyl Formate SCHEMBL27652098 | 0.85 | MEN1 (0.47) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL4620881 | 0.83 | MAPT (0.81) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL10382799 | 0.82 | MEN1 (0.67) | MEN1KMT2AMAPTCYP3A4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412515-A2 | TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE ANTAGONISTS | Genset (FR) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002066672-A2 | TREATMENT OF CNS DISORDERS USING D-AMINO ACID OXIDASE AND D-ASPARTATE OXIDASE ANTAGONISTS | GENSET S.A. (FR) | 2002-08-29 | — | — | WO | disclosed |