Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008542 | 0.93 | STAT3 (0.51) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7005345 | 0.92 | STAT3 (0.47) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL6581474 | 0.91 | STAT3 (0.51) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL20912560 | 0.88 | STAT3 (0.48) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7008215 | 0.88 | STAT3 (0.60) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7008195 | 0.86 | STAT3 (0.52) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7006908 | 0.85 | NPC1 (0.52) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7007126 | 0.84 | STAT3 (0.49) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7008554 | 0.84 | STAT3 (0.49) | STAT3ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL20912596 | 0.82 | STAT3 (0.45) | STAT3ALDH1A1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897919-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6211375-B1 | IMPROVED INTESTINAL ABSORPTION | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0897919-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL AGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-02-24 | — | — | EP | disclosed |