SCHEMBL6581086

SCHEMBL6581086

CCCCN(C(C)=O)c1ccc(C(=O)OCC)c(N(C)C(=O)COC/C=C(\C)CCC=C(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.38
LSS P48449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6581192 0.82 TRPV1 (0.43) TRPV1
SCHEMBL6581186 0.82 TRPV1 (0.43) TRPV1
SCHEMBL6579384 0.82 TRPV1 (0.39) TRPV1
SCHEMBL6579387 0.82 TRPV1 (0.39) TRPV1
SCHEMBL6582096 0.81 TRPV1 (0.37) TRPV1LSS
SCHEMBL6582100 0.81 TRPV1 (0.37) TRPV1LSS
SCHEMBL6582167 0.80 TRPV1 (0.41) TRPV1
SCHEMBL6582176 0.80 TRPV1 (0.41) TRPV1
SCHEMBL7975957 0.79 SMN1; SMN2 (0.45) TRPV1
SCHEMBL7975956 0.79 SMN1; SMN2 (0.45) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927718-B1 Quinolinone derivative, method for preparing the same, and anti-allergic agent DAINIPPON INK & CHEMICALS (JP) 2004-02-25 EP disclosed
US-6271416-B1 O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-08-07 US disclosed
US-6136822-A ETHER, HYDROXY QUINOLINONE COMPOUNDS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-10-24 US disclosed
EP-0927718-A1 Quinolinone derivative, method for preparing the same, and anti-allergic agent DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-07-07 EP disclosed