SCHEMBL6581647

SCHEMBL6581647

COC(=O)CCCCCNC(=O)C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TET2 Q6N021 1/20 0.53
▸ TSHR P16473 3/20 0.52
▸ EPHX2 P34913 6/20 0.51
▸ LMNA P02545 2/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ EGLN1 Q9GZT9 1/20 0.44
▸ RECQL P46063 1/20 0.42
▸ PLA2G2A P14555 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18459815 0.88 TET2 (0.54) TET2ALDH1A1EGLN1PLA2G2A
SCHEMBL17373958 0.85 EGLN1 (0.56) TET2TSHRALDH1A1EGLN1PLA2G2A
SCHEMBL29004439 0.85 TSHR (0.52) TSHREPHX2LMNAALDH1A1RECQL
SCHEMBL29004442 0.85 TSHR (0.52) TSHREPHX2LMNAALDH1A1RECQL
SCHEMBL18724662 0.83 EPHX2 (0.50) TSHREPHX2LMNAALDH1A1RECQL
SCHEMBL21467817 0.83 EPHX2 (0.50) TSHREPHX2LMNAALDH1A1RECQL
SCHEMBL23269433 0.81 EPHX2 (0.49) TSHREPHX2LMNAALDH1A1PLA2G2A
SCHEMBL12332686 0.81 EPHX2 (0.49) TSHREPHX2LMNAALDH1A1PLA2G2A
SCHEMBL16401714 0.80 EPHX2 (0.48) TSHREPHX2LMNAALDH1A1RECQL
SCHEMBL19239219 0.80 TSHR (0.56) TSHREPHX2LMNAALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1414799-A2 HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2004-05-06 — — EP disclosed
US-6727300-B2 PHOTO/THERMAL STABILITY OVER TIME CYTEC TECHNOLOGY CORP. 2004-04-27 — — US disclosed
US-6696570-B2 ESTER/AMIDE HINDERED AMINE LIGHT STABILIZERS (HALS) COMPOUNDS, ESTER/URETHANE HALS COMPOUNDS, ESTER/OXAMATE HALS COMPOUNDS, AMIDE/OXAMIDE HALS COMPOUNDS; PHOTOSTABILITY AND HEAT RESISTANCE FOR POLYMERS CYTEC TECHNOLOGY CORP. 2004-02-24 — — US disclosed
EP-1360177-A2 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME Cytec Technology Corp. (US) 2003-11-12 — — EP disclosed
EP-1337580-A2 POLYMERIC ARTICLES CONTAINING HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS CYTEC TECHNOLOGY CORP. (US) 2003-08-27 — — EP disclosed
EP-1330437-A1 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2003-07-30 — — EP disclosed
US-20030083498-A1 Hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same SASSI THOMAS P (US) 2003-05-01 — — US disclosed
US-6545156-B1 Automobile overcoatings CYTEC TECHNOLOGY CORP. 2003-04-08 — — US disclosed
US-20020161075-A1 Polymeric articles containing hindered amine light stabilizers based on multi-functional carbonyl compounds CYTEC TECHNOLOGY CORP. 2002-10-31 — — US disclosed
WO-2002062885-A2 POLYMERIC ARTICLES CONTAINING HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS CYTEC TECHNOLOGY CORP. (US) 2002-08-15 — — WO disclosed
WO-2002059090-A2 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-08-01 — — WO disclosed
US-20020099218-A1 Hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CYTEC TECHNOLOGY CORP. 2002-07-25 — — US disclosed
WO-2002057234-A1 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-07-25 — — WO disclosed
WO-2002057232-A2 HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-07-25 — — WO disclosed
US-20020087000-A1 Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CYTEC TECHNOLOGY CORP. 2002-07-04 — — US disclosed
US-6414155-B1 STABILIZE POLYMER COMPOSITIONS AGAINST PHOTO- AND THERMAL DEGRADATION CYTEC TECHNOLOGY CORP. 2002-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020087000-A1 Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CBR1, CCNE2, NAF1 TET2 1846/4885TSHR 456/4885EPHX2 157/4885
US-20020099218-A1 Hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CBR1, C1R, CBR3 TET2 1153/4885TSHR 2465/4885EPHX2 1101/4885
US-20030083498-A1 Hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same CBR1, C1R, CBR3 TET2 1091/4885TSHR 2409/4885EPHX2 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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